In remembrance: George Crabtree (1944–2023)

Glucose transport in crabtree-positive and crabtree-negative yeasts.

The kinetic parameters of glucose transport in four Crabtree-positive and four Crabtree-negative yeasts were determined. The organisms were grown in aerobic glucose-limited chemostats at a dilution rate of 0.1 h-1. The results show a clear correlation between the presence of high-affinity glucose transport systems and the absence of aerobic fermentation upon addition of excess glucose to steady...

In remembrance.

“John was an inspiring teacher and experimentalist. His educational passion was creating hands-on experiments built from ordinary parts you can find at any hardware store, what he lovingly called ‘mulch,’” said MIT senior lecturer in physics, and former King student, Peter Dourmashkin ’76 (physics), ’78 (math), PhD ’84. “He was MITx before MITx.” King was born in London and educated in France, ...

The Crabtree effect: a review.

Remembrance of Things Past

an unassuming entrance where once passed Alan Turing, Tommy Flowers, and the thousands of men and women who labored in secrecy. Collectively, they changed the outcome of World War II; individually, the contributions of a few laid the foundations of computing. Until recently, a strong possibility existed that Bletchley Park would be lost to modern development. Thanks to the efforts started by To...

Remembrance of futures past.

Much behavioural and physiological evidence suggests that the hippocampus encodes space. Puzzlingly, however, hippocampal damage also disrupts episodic memory. A recent study shows how these two faculties might be related, finding that the spatial firing of hippocampal 'place cells' is sometimes modulated by what the animal has recently done or what it will do next. Thus, the cells encode somet...